Successful prevention of medication-related osteonecrosis of the jaw after dental extractions by socket preservation with alloplast plus tetracycline in patients taking antiresorptive drugs

The study demonstrates a high prevention effect of socket preservation with alloplast plus tetracycline on reducing MRONJ occurrence after tooth extraction. Enough drug holiday and antimicrobial mouthwash plus systemic antibiotics before and after surgery are recommended. Primary closure is likely unnecessary.

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Publication Details

Journal
Journal of Dental Sciences
Published
2025-10-31
DOI
https://doi.org/10.1016/j.jds.2025.10.020
Primary Topic
Bone health and treatments
Type
article
Field-Weighted Citation Impact
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article

Successful prevention of medication-related osteonecrosis of the jaw after dental extractions by socket preservation with alloplast plus tetracycline in patients taking antiresorptive drugs

Shin-Yu Lu, Chun‐Hsiang Wang, Liang-Ho Lin
Journal of Dental Sciences
Bone health and treatments
article

Successful prevention of medication-related osteonecrosis of the jaw after dental extractions by socket preservation with alloplast plus tetracycline in patients taking antiresorptive drugs

Shin-Yu Lu, Chun‐Hsiang Wang, Liang-Ho Lin
article en

Abstract

The study demonstrates a high prevention effect of socket preservation with alloplast plus tetracycline on reducing MRONJ occurrence after tooth extraction. Enough drug holiday and antimicrobial mouthwash plus systemic antibiotics before and after surgery are recommended. Primary closure is likely unnecessary.

Journal of Dental SciencesVol. 21(1)
Chang Gung University (TW), Chang Gung Memorial Hospital (TW), Kaohsiung Chang Gung Memorial Hospital (TW), National Yunlin University of Science and Technology (TW)
Openalex Percentile: Top 57%
Bone health and treatments
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