Timing of inotropic support is associated with mortality in patients with acute decompensated heart failure-associated cardiogenic shock
Our findings suggest that inotropic support initiated within 8 h of acute presentation is associated with decreased 28-day mortality for patients with ADHF-related cardiogenic shock. Peripheral perfusion and cardiac output measurement were less frequently quantified within the first 24 h for patients with delayed inotropic support. Using shock classification tools, such as the SCAI shock criteria, may help identify patients with CS, especially in its early stages.
Authors
- Jan Bakker (ORCID: https://orcid.org/0000-0003-2236-7391)
- Frances S. Shofer (ORCID: https://orcid.org/0000-0001-6813-4791)
- Joyce Wanglee Wald (ORCID: https://orcid.org/0000-0003-0276-3709)
- David H. Jang (ORCID: https://orcid.org/0000-0002-1213-6971)
- John Augoustides (ORCID: https://orcid.org/0000-0003-3669-158X)
- Moizza Shabbir
- Samantha E. Opitz
- Nova L. Panebianco (ORCID: https://orcid.org/0000-0003-3878-0279)
- Benjamin S. Abella (ORCID: https://orcid.org/0000-0003-2521-0891)
- Wookjin Choi (ORCID: https://orcid.org/0000-0001-8779-0081)
- Charith Ratnayake (ORCID: https://orcid.org/0000-0002-7752-5564)
- John C. Greenwood (ORCID: https://orcid.org/0000-0003-2337-557X)
Institutions
- Hospital of the University of Pennsylvania (US)
- Erasmus MC (NL)
- Ulsan University Hospital (KR)
- University of Pennsylvania (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1186/s40635-025-00806-z
- Citations
- 3
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- University of Pennsylvania
- National Institutes of Health
- National Heart, Lung, and Blood Institute