“Why I Said No”: Trial-Eligible Patient Perspectives on Declining Breast Cancer Clinical Trial Participation
Declining participation in clinical trials is complex and multifactorial. The most cited reasons for declining participation included fear, mistrust, and logistical burdens. These findings highlight the importance of developing targeted strategies to address both emotional and logistical barriers, particularly for vulnerable populations, ensuring that research outcomes are representative, equitable, and generalizable to all patients.
Authors
- Mandy Chen (ORCID: https://orcid.org/0000-0002-1643-2591)
- Nicole L. Henderson (ORCID: https://orcid.org/0000-0003-2101-3065)
- Courtney Williams (ORCID: https://orcid.org/0000-0001-5328-7517)
- Sindhu Dwarampudi
- Lily Gutnik (ORCID: https://orcid.org/0000-0001-8674-7655)
- Gabrielle Betty Rocque (ORCID: https://orcid.org/0000-0003-4188-9785)
- Nicole Reh (ORCID: https://orcid.org/0009-0006-5611-6864)
Institutions
- University of Alabama at Birmingham (US)
- Birmingham VA Medical Center (US)
Publication Details
- Journal
- JCO Oncology Practice
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1200/op-25-00422
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00