Comparative mortality outcomes in metabolic dysfunction-associated steatotic liver disease and nonalcoholic fatty liver disease subtypes in the United States
MASLD is associated with a higher risk of all-cause mortality, and this association is independent of patients' demographic or metabolic characteristics, despite a relatively small hazard ratio. Our research findings further support that MASLD is a pathological disease related to liver disease itself. Therefore, redefining NAFLD as MASLD may help improve our understanding of predictive factors that increase the risk of death.
Authors
- Peipei Yu
- Xianhui Dong (ORCID: https://orcid.org/0000-0003-1761-7923)
- Rong Hu (ORCID: https://orcid.org/0000-0002-3039-0498)
- Chunhong Ye (ORCID: https://orcid.org/0009-0008-0178-1001)
- Pengwei Zhang (ORCID: https://orcid.org/0009-0009-5291-4238)
- Zhiying Che
- Panpan Wang (ORCID: https://orcid.org/0000-0003-4009-1456)
- Tianfang Peng
- Sijia Yang (ORCID: https://orcid.org/0009-0002-3925-9493)
- Yijun Zeng
Institutions
- Hangzhou Normal University (CN)
- Henan University (CN)
- Hubei University of Chinese Medicine (CN)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Jiangxi Applied Engineering Vocational Institute (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1371/journal.pone.0335230
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00