Prevalence and predictors of transfusion-transmitted infections among blood donor types at a teaching hospital in Ghana: Implications for haemovigilance

The high prevalence of TTIs highlights persistent blood safety challenges. Repeat donation was independently protective, reducing risks of HBV, HCV, and syphilis. To improve blood safety, it will be essential to encourage regular voluntary donations. It will also require supplementing RDTs with ELISA where feasible, and strengthening haemovigilance systems, while accounting for the cost and logistical constraints. Although NAT is the gold standard for TTI detection, nationwide implementation in Ghana is currently not feasible.