Oral Ethanol for Methanol Poisoning: A Case Report

Methanol poisoning usually occurs due to accidental ingestion of distilling and fermenting errors or beverage contamination. The typical presentation includes visual disturbances with severe metabolic acidosis and neurological damage. A 32-year-old male presented with blurring of vision for 2 days, with a history of local alcohol consumption 2 days prior, with severe metabolic acidosis on arterial blood gas analysis, and was clinically diagnosed and treated as methanol poisoning in the absence of a serum methanol assay. He responded favorably to the treatment with timely oral ethanol via Nasogastric tube (56 grams, 0.8 g/kg body weight) followed by hemodialysis. His bedside visual acuity was normal, and his complaint of blurred vision subsided on the following day of treatment. This case demonstrates that timely empirical treatment based on clinical suspicion can be life-saving in methanol poisoning, even in the absence of typical diagnostic markers or access to standard antidotal therapy.

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Publication Details

Journal
Journal of Nepal Medical Association
Published
2025-10-31
DOI
https://doi.org/10.31729/jnma.v63i2091.9230
Primary Topic
Poisoning and overdose treatments
Type
article
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article

Oral Ethanol for Methanol Poisoning: A Case Report

Kripa Maharjan, Rony Maharjan
Journal of Nepal Medical Association
Poisoning and overdose treatments
article

Oral Ethanol for Methanol Poisoning: A Case Report

Kripa Maharjan, Rony Maharjan
article en

Abstract

Methanol poisoning usually occurs due to accidental ingestion of distilling and fermenting errors or beverage contamination. The typical presentation includes visual disturbances with severe metabolic acidosis and neurological damage. A 32-year-old male presented with blurring of vision for 2 days, with a history of local alcohol consumption 2 days prior, with severe metabolic acidosis on arterial blood gas analysis, and was clinically diagnosed and treated as methanol poisoning in the absence of a serum methanol assay. He responded favorably to the treatment with timely oral ethanol via Nasogastric tube (56 grams, 0.8 g/kg body weight) followed by hemodialysis. His bedside visual acuity was normal, and his complaint of blurred vision subsided on the following day of treatment. This case demonstrates that timely empirical treatment based on clinical suspicion can be life-saving in methanol poisoning, even in the absence of typical diagnostic markers or access to standard antidotal therapy.

Journal of Nepal Medical AssociationVol. 63(291)
Patan Academy of Health Sciences (NP)
Openalex Percentile: Top 53%
Poisoning and overdose treatments
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