Performance of image-guided bone biopsies in malignant lesions: impact of PET/CT metabolic activity on the number of samples required

This study assessed whether metabolic activity on FDG PET/CT influences the diagnostic yield of IGBB. High metabolic activity did not allow for reducing the number of samples without affecting diagnostic performance. At least three biopsy samples should be obtained, prioritizing safety over metabolic activity when selecting the biopsy site.

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Publication Details

Journal
Insights into Imaging
Published
2025-10-31
DOI
https://doi.org/10.1186/s13244-025-02130-2
Primary Topic
Medical Imaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
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article

Performance of image-guided bone biopsies in malignant lesions: impact of PET/CT metabolic activity on the number of samples required

Vincent Habouzit, P.B. Bonnefoy, Sylvain Grange, Rémi Grange et al.
Insights into Imaging
Medical Imaging Techniques and Applications
article

Performance of image-guided bone biopsies in malignant lesions: impact of PET/CT metabolic activity on the number of samples required

Vincent Habouzit, P.B. Bonnefoy, Sylvain Grange, Rémi Grange, Michel Péoc’h, Claire Boutet, Mathieu Conjeaud
article en

Abstract

This study assessed whether metabolic activity on FDG PET/CT influences the diagnostic yield of IGBB. High metabolic activity did not allow for reducing the number of samples without affecting diagnostic performance. At least three biopsy samples should be obtained, prioritizing safety over metabolic activity when selecting the biopsy site.

Insights into ImagingVol. 16(1)
Inserm (FR), Mines Saint-Étienne (FR), Centre Hospitalier Universitaire de Saint-Étienne (FR)
Openalex Percentile: Top 54%
Medical Imaging Techniques and Applications
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