Integrated analysis identifies CD276 in fibroblasts as a malignancy predictor and regulator of neutrophil infiltration in hepatoblastoma
Our findings highlight the critical role of CD276 in hepatoblastoma malignancy, potentially providing novel insights and therapeutic targets for the development of combinatorial immunotherapy strategies for this disease.
Authors
- Guoqing Zhu (ORCID: https://orcid.org/0000-0002-2731-2018)
- Tianshu Chen (ORCID: https://orcid.org/0000-0002-2053-5307)
- Fenyong Sun (ORCID: https://orcid.org/0000-0003-4959-7138)
- Qiuhui Pan (ORCID: https://orcid.org/0000-0001-7386-2590)
- Miao Ding (ORCID: https://orcid.org/0000-0001-8674-2731)
- Siwei Mao (ORCID: https://orcid.org/0009-0000-0812-1323)
- Ji Ma (ORCID: https://orcid.org/0000-0001-6904-5360)
- Xiaochen Tang (ORCID: https://orcid.org/0009-0007-1526-5238)
- Han Wu
- Jiabei Zhu
- Ni Zhen
Institutions
- Tongji University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Children's Medical Center (CN)
- Shanghai Tenth People's Hospital (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1097/hc9.0000000000000826
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00