Case Report: Massive Upper Gastrointestinal Hemorrhage Due to Spontaneous Gastric Intramural Hematoma

<ns3:p>Spontaneous gastric intramural hematoma (GIH) is an exceptionally rare cause of upper gastrointestinal bleeding. We report the case of a 57-year-old man with no significant medical history who presented with hematemesis, melena, and hemodynamic instability. Upper endoscopy revealed a large submucosal hematoma with active bleeding. Despite endoscopic hemostasis and supportive management, hemorrhage persisted, requiring emergency partial gastrectomy. Histopathological examination confirmed submucosal hemorrhage without evidence of malignancy or vascular malformation. The patient had an uneventful postoperative recovery. This case underscores the importance of considering spontaneous GIH in the differential diagnosis of unexplained upper gastrointestinal bleeding and highlights the role of timely surgical intervention when endoscopic therapy fails.</ns3:p>

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Publication Details

Journal
F1000Research
Published
2025-10-31
DOI
https://doi.org/10.12688/f1000research.172067.1
Primary Topic
Esophageal and GI Pathology
Type
article
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article

Case Report: Massive Upper Gastrointestinal Hemorrhage Due to Spontaneous Gastric Intramural Hematoma

Dhafer Haddad, Nizar Khedhiri, M Sabbah, Meryam Mesbahi et al.
F1000Research
Esophageal and GI Pathology
article

Case Report: Massive Upper Gastrointestinal Hemorrhage Due to Spontaneous Gastric Intramural Hematoma

Dhafer Haddad, Nizar Khedhiri, M Sabbah, Meryam Mesbahi, Haithem Zaafouri, Imen Hlel, Raja Jouini, Nadhira Dhahri
article en

Abstract

<ns3:p>Spontaneous gastric intramural hematoma (GIH) is an exceptionally rare cause of upper gastrointestinal bleeding. We report the case of a 57-year-old man with no significant medical history who presented with hematemesis, melena, and hemodynamic instability. Upper endoscopy revealed a large submucosal hematoma with active bleeding. Despite endoscopic hemostasis and supportive management, hemorrhage persisted, requiring emergency partial gastrectomy. Histopathological examination confirmed submucosal hemorrhage without evidence of malignancy or vascular malformation. The patient had an uneventful postoperative recovery. This case underscores the importance of considering spontaneous GIH in the differential diagnosis of unexplained upper gastrointestinal bleeding and highlights the role of timely surgical intervention when endoscopic therapy fails.</ns3:p>

F1000ResearchVol. 14
Habib hospital Thameur (TN)
Openalex Percentile: Top 50%
Esophageal and GI Pathology
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Case Report: Massive Upper Gastrointestinal Hemorrhage Due to Spontaneous Gastric Intramural Hematoma — Dhafer Haddad, Nizar Khedhiri, et al. · F1000Research (2025) | TGRS Research Map | TGRS