Ginsenoside Re mitigates Aβ1-42-induced neurotoxicity by promoting autophagy and suppressing NLRP3 inflammasome
G-Re ameliorates Aβ<sub>1-42</sub>-induced neuroinflammation and cognitive impairment by restoring mitochondrial homeostasis, enhancing autophagy, and suppressing NLRP3 inflammasome activation. These findings suggest G-Re as a potential therapeutic intervention for neurodegenerative disorders including AD.
Authors
- Yun Hee So (ORCID: https://orcid.org/0009-0007-5721-2636)
- Hyun Seung Shin (ORCID: https://orcid.org/0000-0003-3924-6019)
- Eui‐Man Jung (ORCID: https://orcid.org/0000-0002-1145-402X)
- Iskander Madhi
- Jihee Kim (ORCID: https://orcid.org/0000-0002-0047-5941)
- Young‐Hee Kim (ORCID: https://orcid.org/0000-0001-6582-6290)
Institutions
- Pusan National University (KR)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1016/j.jgr.2025.10.008
- Citations
- 1
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81