<b><i>In silico</i> study: Hepatoprotective effects of capsaicin on the liver of aflatoxin B1-intoxicated mice (<i>Mus musculus</i>)</b>

Capsaicin can synergistically inhibit regulatory cells through the AKT 1 and MAPK 1 signaling pathways, potentiating the hepatotoxicity action protective effect of capsaicin against AFB-1 intoxication. Therefore, capsaicin is a potential candidate for herbal medicine as a hepatoprotective agent.

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Publication Details

Journal
Open Veterinary Journal
Published
2025-01-01
DOI
https://doi.org/10.5455/ovj.2025.v15.i10.50
Primary Topic
Ion Channels and Receptors
Type
article
Field-Weighted Citation Impact
0.00
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article

In silico study: Hepatoprotective effects of capsaicin on the liver of aflatoxin B1-intoxicated mice (Mus musculus)

Adeyinka Oye Akintunde, Sri Pantja Madyawati, Imam Mustofa, Mustofa Helmi Effendi et al.
Open Veterinary Journal
Ion Channels and Receptors
article

In silico study: Hepatoprotective effects of capsaicin on the liver of aflatoxin B1-intoxicated mice (Mus musculus)

Adeyinka Oye Akintunde, Sri Pantja Madyawati, Imam Mustofa, Mustofa Helmi Effendi, Hani Plumeriastuti, Agung Prasetyo, Aswin Rafif Khairullah, Mohammad Sukmanadi, Riza Zainuddin Ahmad, Pudji Srianto, Sri Agus Sudjarwo, Mo Awwanah, Mirni Lamid, Bima Putra Pratama
article en

Abstract

Capsaicin can synergistically inhibit regulatory cells through the AKT 1 and MAPK 1 signaling pathways, potentiating the hepatotoxicity action protective effect of capsaicin against AFB-1 intoxication. Therefore, capsaicin is a potential candidate for herbal medicine as a hepatoprotective agent.

Open Veterinary JournalVol. 15(10)
Universitas Airlangga (ID), Center for Plant Conservation (US), Babcock University (NG)
Openalex Percentile: Top 69%
Ion Channels and Receptors
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<b><i>In silico</i> study: Hepatoprotective effects of capsaicin on the liver of aflatoxin B1-intoxicated mice (<i>Mus musculus</i>)</b> — Adeyinka Oye Akintunde, Sri Pantja Madyawati, et al. · Open Veterinary Journal (2025) | TGRS Research Map | TGRS