<b>Lithium reduces cerebral ischemia/reperfusion injury in dexamethasone-treated rats: The role of the PI3K/Akt pathway</b>

Lithium can protect against CIRI even in the presence of metabolic disturbances, such as those induced by high-dose dexamethasone. The ameliorative effects of lithium were associated with PI3K/Akt pathway upregulation and oxidative stress downregulation.

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Publication Details

Journal
Open Veterinary Journal
Published
2025-01-01
DOI
https://doi.org/10.5455/ovj.2025.v15.i10.41
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Lithium reduces cerebral ischemia/reperfusion injury in dexamethasone-treated rats: The role of the PI3K/Akt pathway

Mona F. Mahmoud, Mohamed Askar, I. H. Ibrahim
Open Veterinary Journal
Neuroinflammation and Neurodegeneration Mechanisms
article

Lithium reduces cerebral ischemia/reperfusion injury in dexamethasone-treated rats: The role of the PI3K/Akt pathway

Mona F. Mahmoud, Mohamed Askar, I. H. Ibrahim
article en

Abstract

Lithium can protect against CIRI even in the presence of metabolic disturbances, such as those induced by high-dose dexamethasone. The ameliorative effects of lithium were associated with PI3K/Akt pathway upregulation and oxidative stress downregulation.

Open Veterinary JournalVol. 15(10)
Zagazig University (EG)
Openalex Percentile: Top 61%
Neuroinflammation and Neurodegeneration Mechanisms
DOIOpen Access PDFOpenAlex
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<b>Lithium reduces cerebral ischemia/reperfusion injury in dexamethasone-treated rats: The role of the PI3K/Akt pathway</b> — Mona F. Mahmoud, Mohamed Askar, et al. · Open Veterinary Journal (2025) | TGRS Research Map | TGRS