Contemporary Methods for Evaluating the Health Impact of Chrysotile-Asbestos on Workers: Scoping review

Analysis of literature data on delayed effects (remote consequences) of exposure to mineral fibers on the body, including chrysotile asbestos, to study the mechanisms by which mineral fibers cause adverse effects in both animals and humans, is a hot topic of interdisciplinary research, many aspects of which are yet to be clarified. The conducted review of scientific literature allowed us to establish a list of pathological conditions in humans and animals that develop later after cessation of contact with various mineral fibers, including chrysotile asbestos. Such conditions (diseases) include pleural mesothelioma, lung cancer, asbestosis, pneumofibrosis, pulmonary emphysema, chronic dust bronchitis, etc. According to literary data, it has been established that workers at enterprises with high occupational dust risks, especially older and elderly people, may develop dust pathology after dismissal, which should be considered as delayed effects of exposure to unfavorable factors. Such production requires more careful attention, study and in-depth analysis of morbidity with temporary loss of ability to work, the results of periodic professional examinations for a quantitative assessment of the magnitude of health risks in various professional groups, the use of modern epidemiological, ecological-hygienic and clinical-diagnostic studies to prevent the development of diseases, premature mortality aimed at increasing the life expectancy of people in industrial regions of the country and after the end of work.