Amomum tsao-ko Crevost et Lemarie extract targets the gut-liver axis to combat atherosclerosis in ApoE−/− mice
T-K has demonstrated significant efficacy in the treatment of atherosclerosis, primarily by lowering serum cholesterol levels and modulating intestinal flora at multiple levels to enhance disease management. Moreover, T-K mitigated the disease progression by attenuating oxidative stress and inflammatory responses in both the liver and aorta.
Authors
- Qianqian Wang
- Zixuan Guo (ORCID: https://orcid.org/0009-0009-5893-0941)
- Junhong Huang (ORCID: https://orcid.org/0000-0003-3245-5870)
- Shuying Feng (ORCID: https://orcid.org/0000-0003-2466-4912)
- Jiamin Zhang (ORCID: https://orcid.org/0000-0001-5919-002X)
- Boyi Zhang (ORCID: https://orcid.org/0000-0002-4884-5147)
- Jiawei Huang (ORCID: https://orcid.org/0000-0003-4390-2584)
- Yuanyuan Niu (ORCID: https://orcid.org/0000-0002-5599-6031)
Institutions
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-10-31
- DOI
- https://doi.org/10.3389/fmicb.2025.1641035
- Primary Topic
- Ginger and Zingiberaceae research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Henan Province