Association between obesity indices, insulin resistance markers, and osteoarthritis in middle-aged and elderly Chinese adults
Obesity-related indicators and IR surrogates are significantly associated with OA risk. Among these, TyG-WHtR demonstrates the strongest predictive performance, suggesting its potential as an early screening tool for OA. This study highlights obesity and IR as modifiable risk factors, providing a basis for the early prevention and control of OA.
Authors
- Jianxin Zhou (ORCID: https://orcid.org/0000-0003-2111-2127)
- Suyao Zhang
- Zhen Jiang
- H Liao (ORCID: https://orcid.org/0000-0003-2168-706X)
- Haibo Wang (ORCID: https://orcid.org/0000-0003-0955-9532)
- Huwei Bian (ORCID: https://orcid.org/0000-0001-9696-5330)
- Tao Jiang (ORCID: https://orcid.org/0009-0007-6524-5382)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Changzhou No.2 People's Hospital (CN)
- Changzhou University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-10-31
- DOI
- https://doi.org/10.3389/fnut.2025.1627421
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00