Recombination events restored the functional horned haplotypes in the offspring of polled parents

We show that different genomic arrangements in the POLLED locus can lead to the emergence of de novo ancestral horn phenotypes. Such arrangements can complicate phenotype prediction in offspring, even when sires or dams have been tested as genetically homozygous polled. Therefore, it is important, for a better understanding of the relationship between the POLLED locus and the POLLED phenotype, that any deviation from the expected result is critically analysed. Possibly, some of these cases can further narrow down the sequence motif that is essential for polledness in cattle.

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Publication Details

Journal
Genetics Selection Evolution
Published
2025-10-31
DOI
https://doi.org/10.1186/s12711-025-01009-6
Primary Topic
Plant Reproductive Biology
Type
article
Field-Weighted Citation Impact
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article

Recombination events restored the functional horned haplotypes in the offspring of polled parents

Alexander Graf, Ingolf Ruß, Neža Pogorevc, Maulik Upadhyay et al.
Genetics Selection Evolution
Plant Reproductive Biology
article

Recombination events restored the functional horned haplotypes in the offspring of polled parents

Alexander Graf, Ingolf Ruß, Neža Pogorevc, Maulik Upadhyay, Ivica Međugorac, Doris Seichter, S. Meier, Stefan Krebs
article en

Abstract

We show that different genomic arrangements in the POLLED locus can lead to the emergence of de novo ancestral horn phenotypes. Such arrangements can complicate phenotype prediction in offspring, even when sires or dams have been tested as genetically homozygous polled. Therefore, it is important, for a better understanding of the relationship between the POLLED locus and the POLLED phenotype, that any deviation from the expected result is critically analysed. Possibly, some of these cases can further narrow down the sequence motif that is essential for polledness in cattle.

Genetics Selection EvolutionVol. 57(1)
LMU Klinikum (DE), ID Genomics (United States) (US), Munich Security Conference (DE), Synergetics (Belgium) (BE), Max Planck Institute of Biochemistry (DE), Ludwig-Maximilians-Universität München (DE)
Openalex Percentile: Top 72%
Plant Reproductive Biology
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