Pediatric Ménétrier’s Disease Triggered by <i>Cytomegalovirus</i> Infection: A Rare Case of Severe Hypoalbuminemia and Edema

This case reinforces the known association between CMV and MD in children and highlights the variability of CMV detection via PCR or serology. Although pediatric MD is often self-limiting, antiviral therapy may be indicated in severe cases or when supportive care is insufficient. The presence of hypogammaglobulinemia in this case also raises questions about potential underlying immunodeficiency. Clinicians should maintain a high index of suspicion for CMV-associated MD in children with acute-onset edema and hypoalbuminemia, even when routine viral testing is negative.

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Publication Details

Journal
Case Reports in Pediatrics
Published
2025-01-01
DOI
https://doi.org/10.1155/crpe/2471369
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
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article

Pediatric Ménétrier’s Disease Triggered by Cytomegalovirus Infection: A Rare Case of Severe Hypoalbuminemia and Edema

Mutaz Sultan, Sami Bannoura, Issa Snoubar, Tariq Alhendi et al.
Case Reports in Pediatrics
Cytomegalovirus and herpesvirus research
article

Pediatric Ménétrier’s Disease Triggered by Cytomegalovirus Infection: A Rare Case of Severe Hypoalbuminemia and Edema

Mutaz Sultan, Sami Bannoura, Issa Snoubar, Tariq Alhendi, Dalia Batanji, Noor Nabresi, Kamaledein Einar
article en

Abstract

This case reinforces the known association between CMV and MD in children and highlights the variability of CMV detection via PCR or serology. Although pediatric MD is often self-limiting, antiviral therapy may be indicated in severe cases or when supportive care is insufficient. The presence of hypogammaglobulinemia in this case also raises questions about potential underlying immunodeficiency. Clinicians should maintain a high index of suspicion for CMV-associated MD in children with acute-onset edema and hypoalbuminemia, even when routine viral testing is negative.

Case Reports in PediatricsVol. 2025(1)
The University of Texas MD Anderson Cancer Center (US), An-Najah National University (PS), Palestine Technical University - Kadoorie (PS), Al-Makassed Islamic Charitable Society Hospital (IL)
Openalex Percentile: Top 58%
Cytomegalovirus and herpesvirus research
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