Medical Feature Extraction From Clinical Examination Notes: Development and Evaluation of a Two-Phase Large Language Model Framework

Our two-phase LLM framework successfully addresses critical challenges in automated medical feature extraction, achieving state-of-the-art performance while reducing hallucination and missing features. The framework's ability to achieve high performance with minimal training data (F<sub>1</sub>=0.960-0.973 with 100 samples) demonstrates strong generalization capabilities essential for resource-constrained settings in medical education. While traditional calibration metrics show misalignment, the practical benefits of confidence injection led to reduced errors, and inference-time filtering provided reliable outputs suitable for automated clinical assessment applications.

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Publication Details

Journal
JMIR Medical Informatics
Published
2025-10-31
DOI
https://doi.org/10.2196/78432
Primary Topic
Machine Learning in Healthcare
Type
article
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article

Medical Feature Extraction From Clinical Examination Notes: Development and Evaluation of a Two-Phase Large Language Model Framework

Mahmoud Ragab, Abdullah Alghamdi, Ayman G. Fayoumi, Manal Abumelha
JMIR Medical Informatics
Machine Learning in Healthcare
article

Medical Feature Extraction From Clinical Examination Notes: Development and Evaluation of a Two-Phase Large Language Model Framework

Mahmoud Ragab, Abdullah Alghamdi, Ayman G. Fayoumi, Manal Abumelha
article en

Abstract

Our two-phase LLM framework successfully addresses critical challenges in automated medical feature extraction, achieving state-of-the-art performance while reducing hallucination and missing features. The framework's ability to achieve high performance with minimal training data (F<sub>1</sub>=0.960-0.973 with 100 samples) demonstrates strong generalization capabilities essential for resource-constrained settings in medical education. While traditional calibration metrics show misalignment, the practical benefits of confidence injection led to reduced errors, and inference-time filtering provided reliable outputs suitable for automated clinical assessment applications.

JMIR Medical InformaticsVol. 13
King Abdulaziz University (SA), Dar Al-Hekma University (SA), King Khalid University (SA)
Openalex Percentile: Top 83%
Machine Learning in Healthcare
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Medical Feature Extraction From Clinical Examination Notes: Development and Evaluation of a Two-Phase Large Language Model Framework — Mahmoud Ragab, Abdullah Alghamdi, et al. · JMIR Medical Informatics (2025) | TGRS Research Map | TGRS