Transcriptomics combined with in vitro experimental validation probes polyamine metabolic profiles in low-grade gliomas
This study elucidates the underlying mechanisms of the molecular regulation of polyamine metabolism and its value for the clinical prognosis of LGG, with the key gene SMS playing a significant role in promoting the malignant progression of glioma cells.
Authors
- Chaoqun Lian (ORCID: https://orcid.org/0000-0003-4914-020X)
- Xinyu Zhang (ORCID: https://orcid.org/0000-0002-5979-244X)
- Huili Chen (ORCID: https://orcid.org/0000-0001-5828-2942)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-5346-7566)
- Linfeng Pan (ORCID: https://orcid.org/0000-0003-0398-7333)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tcr-2025-776
- Primary Topic
- Polyamine Metabolism and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00