A novel prognostic tool for triple-negative breast cancer: creating and testing a parthanatos-related gene model
Through systematic analysis, we developed a 12 PR-mRNAs signature that effectively predicts clinical outcomes in TNBC patients. The newly established risk assessment model not only provides a reliable tool for prognostic evaluation but also reveals NECTIN2 as a clinically significant biomarker, with elevated expression correlating with poorer survival outcomes.
Authors
- Gang Wu (ORCID: https://orcid.org/0000-0002-4764-8272)
- Dezhi Mu (ORCID: https://orcid.org/0000-0002-2599-7041)
- Jiahong Sun
- Jiandong Wang (ORCID: https://orcid.org/0000-0002-5079-1459)
- Siyi Chen (ORCID: https://orcid.org/0000-0002-0153-6152)
- Zitong Yang
Institutions
- Tumor Hospital of Guangxi Medical University (CN)
- PLA Academy of Military Science (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tcr-2025-819
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00