KRT23 promotes proliferation invasion and metastasis of gastric cancer through epithelial-mesenchymal transition mediated by the PI3K/AKT/mTOR signaling pathway
KRT23 is highly expressed in GC tissues. Knockdown of KRT23 can significantly suppress the proliferation, migration, and invasion of GC cells, and its mechanism might be closely related to the PI3K/AKT/mTOR signaling pathway.
Authors
- Fanghui Zhou (ORCID: https://orcid.org/0000-0002-7491-2614)
- Yi Xie (ORCID: https://orcid.org/0000-0003-2150-8973)
- Pailan Peng
- Xuelian Li (ORCID: https://orcid.org/0000-0001-9043-8580)
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tcr-2025-872
- Primary Topic
- Skin and Cellular Biology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00