The role of liquid-liquid phase separation in hepatocellular carcinoma: single-cell analysis and identification of prognostic biomarkers
We developed a model that can accurately predict the outcomes of patients with HCC, clarified the mechanisms underlying the LLPSRS's relationship to HCC, and generated findings that contribute to the personalized treatment and development of immunotherapy for patients with HCC.
Authors
- Lei Shi (ORCID: https://orcid.org/0000-0003-2627-7588)
- Xiaowei Tang (ORCID: https://orcid.org/0000-0001-6064-0526)
- Rui Luo (ORCID: https://orcid.org/0000-0001-5280-0999)
- Shu Huang (ORCID: https://orcid.org/0000-0003-2825-9180)
- Jieyu Peng
- Qi Chen (ORCID: https://orcid.org/0000-0001-6353-9589)
- Shiqi Li (ORCID: https://orcid.org/0000-0001-9949-0692)
- Lei Wang (ORCID: https://orcid.org/0000-0002-3368-2832)
- Xiaomin Shi
- Yan Peng (ORCID: https://orcid.org/0000-0002-4007-0850)
- Wei Zhang (ORCID: https://orcid.org/0000-0003-4950-3242)
- Xiaohong Wang
Institutions
- Xuzhou Medical College (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Second People’s Hospital of Huai’an (CN)
- Xuzhou Central Hospital (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/tcr-2025-726
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00