A narrative literature review on the clinical utility of activated partial thromboplastin time and anti-factor Xa activity assays in cancer patients with anticoagulant therapy

A synergistic approach combining both assays, tailored to the specific anticoagulant, patient factors, and clinical context, appears optimal for evidence-based, individualized anticoagulation management in cancer patients. Future large-scale trials are needed to validate correlations between monitoring results and clinical endpoints.

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Publication Details

Journal
Translational Cancer Research
Published
2025-10-01
DOI
https://doi.org/10.21037/tcr-2025-1944
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
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article

A narrative literature review on the clinical utility of activated partial thromboplastin time and anti-factor Xa activity assays in cancer patients with anticoagulant therapy

Jie Zhao, Yanhong Chen, Xiaofang Zhang, Lihong Song et al.
Translational Cancer Research
Venous Thromboembolism Diagnosis and Management
article

A narrative literature review on the clinical utility of activated partial thromboplastin time and anti-factor Xa activity assays in cancer patients with anticoagulant therapy

Jie Zhao, Yanhong Chen, Xiaofang Zhang, Lihong Song, Haixin Li
article en

Abstract

A synergistic approach combining both assays, tailored to the specific anticoagulant, patient factors, and clinical context, appears optimal for evidence-based, individualized anticoagulation management in cancer patients. Future large-scale trials are needed to validate correlations between monitoring results and clinical endpoints.

Translational Cancer ResearchVol. 14(10)
Handan College (CN)
Openalex Percentile: Top 48%
Venous Thromboembolism Diagnosis and Management
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A narrative literature review on the clinical utility of activated partial thromboplastin time and anti-factor Xa activity assays in cancer patients with anticoagulant therapy — Jie Zhao, Yanhong Chen, et al. · Translational Cancer Research (2025) | TGRS Research Map | TGRS