A Simplified Novel Algorithm to Predict the 21-Gene Recurrence Score

This simplified algorithm accurately predicts Oncotype DX RS category using only histologic grade and PR%. It enables confident risk stratification in most patients without molecular testing, offering a low-cost, practical tool for clinical decision-making, particularly in resource-limited settings.

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Publication Details

Journal
World Journal of Oncology
Published
2025-10-31
DOI
https://doi.org/10.14740/wjon2634
Primary Topic
Genomic variations and chromosomal abnormalities
Type
article
Field-Weighted Citation Impact
0.00
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article

A Simplified Novel Algorithm to Predict the 21-Gene Recurrence Score

Maher A. Sughayer, Ahmad Alsughayer, Bayan Maraqa, Hikmat Abdel-Razeq et al.
World Journal of Oncology
Genomic variations and chromosomal abnormalities
article

A Simplified Novel Algorithm to Predict the 21-Gene Recurrence Score

Maher A. Sughayer, Ahmad Alsughayer, Bayan Maraqa, Hikmat Abdel-Razeq, Batool Qura'an
article en

Abstract

This simplified algorithm accurately predicts Oncotype DX RS category using only histologic grade and PR%. It enables confident risk stratification in most patients without molecular testing, offering a low-cost, practical tool for clinical decision-making, particularly in resource-limited settings.

World Journal of OncologyVol. 16(6)
King Hussein Cancer Center (JO), Ministry of Health (JO)
Openalex Percentile: Top 66%
Genomic variations and chromosomal abnormalities
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