Reduced Peripheral Blood Natural Killer Cell Proportion Predicts Poor Overall Survival in Advanced Gastric Cancer Patients Treated With Apatinib
Apatinib combined with S-1 exhibited favorable tolerability and promising clinical activity as a second-line option for AGC patients. Importantly, we identified peripheral blood NK cell proportion as a potential predictor of treatment response, where a low NK cell proportion correlated with poorer outcomes.
Authors
- Niu Zhang
- Geng Tian (ORCID: https://orcid.org/0000-0001-9939-7287)
- Ye Qing Zhang
- Sheng Hu (ORCID: https://orcid.org/0000-0002-2709-6976)
- Yan Wang (ORCID: https://orcid.org/0000-0003-2057-0097)
- Yu Ting Wang
- Hui Shan
- Zhiquan Qiu (ORCID: https://orcid.org/0009-0003-8383-2776)
Institutions
- Jiangsu University (CN)
- Soochow University (CN)
- Affiliated Hospital of Jiangsu University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- World Journal of Oncology
- Published
- 2025-10-31
- DOI
- https://doi.org/10.14740/wjon2655
- Citations
- 1
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Jiangsu University