Detection and characterization of multidrug-resistant Klebsiella spp. and Enterobacter spp. isolates in Colombian guinea pigs intended for human consumption
This study provides the first evidence in Colombia of MDR <i>Klebsiella</i> spp. and <i>Enterobacter</i> spp. isolates carrying clinically important resistance genes in guinea pigs intended for human consumption. The detection of carbapenemase genes (<i>bla<sub>KPC</sub></i> and <i>bla<sub>OXA-48</sub></i> ) is particularly concerning given their role in limiting therapeutic options. These findings highlight the urgent need for improved antimicrobial stewardship, stricter regulation of antibiotic use in guinea pig production systems, enhanced surveillance, and targeted farmer education to mitigate AMR risks at the human-animal interface.
Authors
- Valéria Dutra (ORCID: https://orcid.org/0000-0002-6630-2293)
- Tatiana Gabriela Paz Calvache (ORCID: https://orcid.org/0000-0001-5852-1317)
- Sofia Juliana Merchancano Bravo (ORCID: https://orcid.org/0009-0004-5733-9723)
Institutions
- University of Nariño (CO)
- Universidade Federal de Mato Grosso (BR)
Publication Details
- Journal
- Veterinary World
- Published
- 2025-10-01
- DOI
- https://doi.org/10.14202/vetworld.2025.3187-3196
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Mato Grosso
- Division of Graduate Education