“Off‐The‐Shelf” Bioartificial Liver Support System Using Cryopreserved Immobilized Hepatocyte Spheroids in a Porcine Acute Liver Failure Model
A BAL system with a bioreactor containing cryopreserved immobilized hepatocyte spheroids showed effective clearance of serum ammonia, preservation of renal function, and improved survival in a porcine model of ALF.
Authors
- Young‐A Kim (ORCID: https://orcid.org/0000-0001-8108-4880)
- Doo‐Hoon Lee
- Suk‐Koo Lee (ORCID: https://orcid.org/0000-0002-8503-2882)
- Ji‐Hyun Lee (ORCID: https://orcid.org/0000-0003-1098-1984)
- Sunghoon Lee (ORCID: https://orcid.org/0000-0002-3592-388X)
- Hee‐Hoon Yoon
Institutions
- Samsung Medical Center (KR)
- Myongji Hospital (KR)
- Dae Hwa Pharm (South Korea) (KR)
Publication Details
- Journal
- Artificial Organs
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1111/aor.70034
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Samsung