Nomogram model based on magnetic resonance imaging and clinical factors for prenatal diagnosis of placenta accreta spectrum disorders

This study aimed to develop a magnetic resonance imaging (MRI) and clinical factor-based nomogram for prenatal diagnosis of placenta accreta spectrum disorders (PAS). Clinical and MRI data from pregnant women were retrospectively analyzed and split into training (70%) and validation (30%) sets. Binary logistic regression identified age, placenta previa, T2 dark band, placental/uterine bulge, loss of T2 hypointense interface, myometrial thinning, and abnormal placental bed vessels as significant predictors of PAS. A nomogram incorporating these factors demonstrated strong diagnostic performance via ROC analysis (AUC >0.8), calibration curves, and decision curve analysis (DCA) in both training and validation sets. The model showed high accuracy and clinical utility, supporting its use in prenatal PAS diagnosis.

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Publication Details

Journal
African Journal of Reproductive Health
Published
2025-10-31
DOI
https://doi.org/10.29063/ajrh2025/v29i10.16
Citations
1
Primary Topic
Maternal and fetal healthcare
Type
article
Field-Weighted Citation Impact
3.49

Funders

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article

Nomogram model based on magnetic resonance imaging and clinical factors for prenatal diagnosis of placenta accreta spectrum disorders

Peipei Lin, Dandan Miao, Qin Zhang, Jingjing Zhong et al.
1 citations
African Journal of Reproductive Health
Maternal and fetal healthcare
3.49
article

Nomogram model based on magnetic resonance imaging and clinical factors for prenatal diagnosis of placenta accreta spectrum disorders

Peipei Lin, Dandan Miao, Qin Zhang, Jingjing Zhong, Honggang Yin
article en
1 citations

Abstract

This study aimed to develop a magnetic resonance imaging (MRI) and clinical factor-based nomogram for prenatal diagnosis of placenta accreta spectrum disorders (PAS). Clinical and MRI data from pregnant women were retrospectively analyzed and split into training (70%) and validation (30%) sets. Binary logistic regression identified age, placenta previa, T2 dark band, placental/uterine bulge, loss of T2 hypointense interface, myometrial thinning, and abnormal placental bed vessels as significant predictors of PAS. A nomogram incorporating these factors demonstrated strong diagnostic performance via ROC analysis (AUC >0.8), calibration curves, and decision curve analysis (DCA) in both training and validation sets. The model showed high accuracy and clinical utility, supporting its use in prenatal PAS diagnosis.

African Journal of Reproductive HealthVol. 29(10)
Nantong University (CN), Nantong Maternity and Child Health Hospital (CN)
Nantong University
Openalex Percentile: Top 6%
Maternal and fetal healthcare
3.49
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Nomogram model based on magnetic resonance imaging and clinical factors for prenatal diagnosis of placenta accreta spectrum disorders — Peipei Lin, Dandan Miao, et al. · African Journal of Reproductive Health (2025) | TGRS Research Map | TGRS