Nomogram model based on magnetic resonance imaging and clinical factors for prenatal diagnosis of placenta accreta spectrum disorders
This study aimed to develop a magnetic resonance imaging (MRI) and clinical factor-based nomogram for prenatal diagnosis of placenta accreta spectrum disorders (PAS). Clinical and MRI data from pregnant women were retrospectively analyzed and split into training (70%) and validation (30%) sets. Binary logistic regression identified age, placenta previa, T2 dark band, placental/uterine bulge, loss of T2 hypointense interface, myometrial thinning, and abnormal placental bed vessels as significant predictors of PAS. A nomogram incorporating these factors demonstrated strong diagnostic performance via ROC analysis (AUC >0.8), calibration curves, and decision curve analysis (DCA) in both training and validation sets. The model showed high accuracy and clinical utility, supporting its use in prenatal PAS diagnosis.
Authors
- Peipei Lin (ORCID: https://orcid.org/0000-0001-9920-1061)
- Dandan Miao
- Qin Zhang (ORCID: https://orcid.org/0000-0002-9845-4099)
- Jingjing Zhong
- Honggang Yin
Institutions
- Nantong University (CN)
- Nantong Maternity and Child Health Hospital (CN)
Publication Details
- Journal
- African Journal of Reproductive Health
- Published
- 2025-10-31
- DOI
- https://doi.org/10.29063/ajrh2025/v29i10.16
- Citations
- 1
- Primary Topic
- Maternal and fetal healthcare
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Nantong University