Comparison of the predictive performance of Cumulative Illness Rating Scale, Charlson Comorbidity Index and COMCOLD Index for moderate-to-severe exacerbations in elderly subjects with chronic obstructive pulmonary disease
CIRS provides superior prognostic accuracy compared to established comorbidity indices in identifying COPD patients at increased risk of exacerbations. These findings highlight the clinical relevance of incorporating a comprehensive, severity-weighted comorbidity assessment in COPD management, supporting the concept of COPD as a complex, multisystem disorder requiring an integrated approach to care.
Authors
- Lucio D’Anna (ORCID: https://orcid.org/0000-0002-4349-3322)
- Antonino Tuttolomondo (ORCID: https://orcid.org/0000-0001-6440-7318)
- Davide Paolo Bernasconi (ORCID: https://orcid.org/0000-0001-8771-5428)
- Edoardo Pirera (ORCID: https://orcid.org/0000-0003-3011-7405)
- Riccardo De Rosa
- Domenico Di Raimondo (ORCID: https://orcid.org/0000-0002-4529-3703)
- Sergio Ferrantelli
- Martina Profita
Institutions
- Imperial College Healthcare NHS Trust (GB)
- Charing Cross Hospital (GB)
- Department of Health (ES)
- Imperial College London (GB)
- University of Milano-Bicocca (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1080/07853890.2025.2579789
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00