Acquired syphilis in a 3-year-old boy: a case report

A 3-year-old boy with atypical skin lesions was diagnosed with syphilis, probably acquired through close daily contact with his grandparents. The case highlights the critical need for syphilis testing in children with non-specific skin findings, particularly when familial exposure is suspected. Physicians should prioritise thorough assessment, including detailed enquiry into the child's medical history, feeding practices, lifestyle and potential exposure to infection. Prompt screening of close contacts including family members and carers is essential in order to identify infection sources and prevent further transmission.<b>Abbreviations</b>: ANA: Antinuclear antibody; ESR: Erythrocyte sedimentation rate; RPR: Rapid plasma reagin; TPPA: <i>T. pallidum</i> particle agglutination.

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Publication Details

Journal
Paediatrics and International Child Health
Published
2025-10-02
DOI
https://doi.org/10.1080/20469047.2025.2580798
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Acquired syphilis in a 3-year-old boy: a case report

Changxia Li, Xiaohua Tao, Shiyang Li, Yi Xu
Paediatrics and International Child Health
Syphilis Diagnosis and Treatment
article

Acquired syphilis in a 3-year-old boy: a case report

Changxia Li, Xiaohua Tao, Shiyang Li, Yi Xu
article en

Abstract

A 3-year-old boy with atypical skin lesions was diagnosed with syphilis, probably acquired through close daily contact with his grandparents. The case highlights the critical need for syphilis testing in children with non-specific skin findings, particularly when familial exposure is suspected. Physicians should prioritise thorough assessment, including detailed enquiry into the child's medical history, feeding practices, lifestyle and potential exposure to infection. Prompt screening of close contacts including family members and carers is essential in order to identify infection sources and prevent further transmission.<b>Abbreviations</b>: ANA: Antinuclear antibody; ESR: Erythrocyte sedimentation rate; RPR: Rapid plasma reagin; TPPA: <i>T. pallidum</i> particle agglutination.

Paediatrics and International Child HealthVol. 45(3-4)
Nanchang University (CN), National Clinical Research Center for Digestive Diseases (CN), Jiangxi Provincial People's Hospital (CN), Second Affiliated Hospital of Nanchang University (CN), Jiangxi Chest Hospital (CN), Jiangxi Provincial Institute of Water Sciences (CN), National Clinical Research (US), First Affiliated Hospital of Nanchang University (CN)
Openalex Percentile: Top 60%
Syphilis Diagnosis and Treatment
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