Optimizing Micafungin Dosing in Patients with Critically Ill Candidemia and Trends of Candida Species Causing Bloodstream Infections in a Tertiary Hospital in Thailand: A Monte Carlo Simulation Approach

Non-<i>albicans Candida</i> bloodstream infections are increasing, along with higher MIC trends, signaling emerging resistance. Standard dosing may be insufficient in critically ill patients. Empirical high-dose micafungin could improve treatment efficacy.

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Journal
Drug Design Development and Therapy
Published
2025-10-01
DOI
https://doi.org/10.2147/dddt.s549066
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00

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article

Optimizing Micafungin Dosing in Patients with Critically Ill Candidemia and Trends of Candida Species Causing Bloodstream Infections in a Tertiary Hospital in Thailand: A Monte Carlo Simulation Approach

Adisak Sangchankoom, Worawong Chueansuwan, Weerayuth Saelim, Piraporn Juntanawiwat et al.
Drug Design Development and Therapy
Antifungal resistance and susceptibility
article

Optimizing Micafungin Dosing in Patients with Critically Ill Candidemia and Trends of Candida Species Causing Bloodstream Infections in a Tertiary Hospital in Thailand: A Monte Carlo Simulation Approach

Adisak Sangchankoom, Worawong Chueansuwan, Weerayuth Saelim, Piraporn Juntanawiwat, Nuntra Suwantarat, Wichai Santimaleeworagun, Jutharat Watcharasuwanseree
article en

Abstract

Non-<i>albicans Candida</i> bloodstream infections are increasing, along with higher MIC trends, signaling emerging resistance. Standard dosing may be insufficient in critically ill patients. Empirical high-dose micafungin could improve treatment efficacy.

Drug Design Development and TherapyVol. Volume 19
Thammasat University (TH), Thammasat University Hospital (TH), Hodges University (US), Phramongkutklao Hospital (TH), Suratthani Cancer Hospital (TH), Udon Thani Hospital (TH), Silpakorn University (TH)
Thammasat University
Openalex Percentile: Top 63%
Antifungal resistance and susceptibility
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Optimizing Micafungin Dosing in Patients with Critically Ill Candidemia and Trends of Candida Species Causing Bloodstream Infections in a Tertiary Hospital in Thailand: A Monte Carlo Simulation Approach — Adisak Sangchankoom, Worawong Chueansuwan, et al. · Drug Design Development and Therapy (2025) | TGRS Research Map | TGRS