Impact of genetic variation in the human leptin gene promoter on metabolic dysfunction-associated steatotic liver disease risk
For the first time, our findings demonstrated that the "GG" genotype of LEP -2548G>A gene variant can be a potential protective factor for MASLD. Further studies in other populations, however, are required to support this finding.
Authors
- Gholamreza Rezamand (ORCID: https://orcid.org/0000-0002-4305-2420)
- Aidin Mahban (ORCID: https://orcid.org/0000-0002-7994-5597)
- Reza Dabiri (ORCID: https://orcid.org/0000-0003-4506-9901)
- Asadollah Asadi (ORCID: https://orcid.org/0000-0003-3314-2948)
- Hamid Farahani (ORCID: https://orcid.org/0000-0002-1262-1854)
- Seidamir Pasha Tabaeian (ORCID: https://orcid.org/0000-0001-5260-5667)
- Touraj Mahmoudi (ORCID: https://orcid.org/0000-0002-3220-6252)
- Hossein Nobakht (ORCID: https://orcid.org/0000-0001-9386-2280)
- Nikta Zafarjafarzadeh (ORCID: https://orcid.org/0000-0002-5020-797X)
- Fatemeh Ghasemi (ORCID: https://orcid.org/0009-0004-5960-448X)
- Mobina Hosseini (ORCID: https://orcid.org/0000-0003-4665-5662)
- Mitra Rostami (ORCID: https://orcid.org/0009-0002-5162-1256)
- Atefeh Dehghanitafti (ORCID: https://orcid.org/0000-0002-1700-7175)
- Kosar Babaeian Roshani (ORCID: https://orcid.org/0000-0002-3182-6417)
- Amirhesam Mashaollahi (ORCID: https://orcid.org/0000-0003-2037-5355)
- Zahra Ourang (ORCID: https://orcid.org/0009-0002-5700-1090)
Institutions
- Islamic Azad University, Science and Research Branch (IR)
- Iran University of Medical Sciences (IR)
- Semnan University of Medical Sciences (IR)
- Shahid Beheshti University of Medical Sciences (IR)
- Qom University of Medical Science and Health Services (IR)
- University of Mohaghegh Ardabili (IR)
Publication Details
- Journal
- Archives of Endocrinology and Metabolism
- Published
- 2025-01-01
- DOI
- https://doi.org/10.20945/2359-4292-2024-0458
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.00