Exploring the role of onchocerciasis in epilepsy: insights from a mouse model study
This study explored how Onchocerca ochengi, a parasite, affects brain function and behavior in mice, as a way to understand epilepsy linked to parasitic infections in humans. The infected mice showed weight loss, anxiety-like behavior and memory problems early on, which later improved over time. These findings may help explain how parasitic infections can contribute to neurological conditions like epilepsy.
Authors
- Fidelis Cho‐Ngwa (ORCID: https://orcid.org/0000-0001-8529-8771)
- Stephen Mbigha Ghogomu (ORCID: https://orcid.org/0000-0003-3459-6554)
- Rene Bilingwe Ayiseh (ORCID: https://orcid.org/0000-0001-5308-1666)
- Blendin Gemuh Serri (ORCID: https://orcid.org/0009-0009-5448-4833)
- Lewis Enchaw Enchaw
Institutions
- University of Buea (CM)
Publication Details
- Journal
- Transactions of the Royal Society of Tropical Medicine and Hygiene
- Published
- 2025-10-08
- DOI
- https://doi.org/10.1093/trstmh/traf115
- Primary Topic
- Parasitic Diseases Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00