A Retrospective Analysis of the Efficacy and Safety of Imatinib for Advanced Gastrointestinal Stromal Tumor in Elderly Patients

Imatinib is an effective treatment for advanced GIST in elderly patients. However, elderly patients were associated with poorer efficacy and a Higher incidence of toxicities due to imatinib compared with non-elderly patients.

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Publication Details

Journal
Cancer Medicine
Published
2025-10-31
DOI
https://doi.org/10.1002/cam4.71338
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A Retrospective Analysis of the Efficacy and Safety of Imatinib for Advanced Gastrointestinal Stromal Tumor in Elderly Patients

Atsuo Takashima, Kengo Nagashima, Takahito Awatsu, Hidekazu Hirano et al.
Cancer Medicine
Gastrointestinal Tumor Research and Treatment
article

A Retrospective Analysis of the Efficacy and Safety of Imatinib for Advanced Gastrointestinal Stromal Tumor in Elderly Patients

Atsuo Takashima, Kengo Nagashima, Takahito Awatsu, Hidekazu Hirano, Akihito Nagahara, Natsuko Okita, Ken Kato, Hirokazu Shoji, Toshiharu Hirose
article en

Abstract

Imatinib is an effective treatment for advanced GIST in elderly patients. However, elderly patients were associated with poorer efficacy and a Higher incidence of toxicities due to imatinib compared with non-elderly patients.

Cancer MedicineVol. 14(21)
Juntendo University (JP), Keio University Hospital (JP), National Cancer Center Hospital East (JP)
Openalex Percentile: Top 55%
Gastrointestinal Tumor Research and Treatment
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A Retrospective Analysis of the Efficacy and Safety of Imatinib for Advanced Gastrointestinal Stromal Tumor in Elderly Patients — Atsuo Takashima, Kengo Nagashima, et al. · Cancer Medicine (2025) | TGRS Research Map | TGRS