Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension

In a population with mild-to-moderate hypertension, long-term therapy with GMRx2-based treatment achieved high levels of BP control and was well tolerated.Trial registration: NCT04518306.

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Publication Details

Journal
Global Heart
Published
2025-10-31
DOI
https://doi.org/10.5334/gh.1481
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension

Suzanne Oparil, Christopher Gianacas, William C. Cushman, Diederick E. Grobbee et al.
Global Heart
Diabetes Treatment and Management
article

Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension

Suzanne Oparil, Christopher Gianacas, William C. Cushman, Diederick E. Grobbee, Godwin Constantine, Wilko Spiering, Anthony Rodgers, Dike Bevis Ojji, Bryan Williams, Tiago Pereira, Mahmoud Umar Sani, Ruth S. Freed, T. Kumanan‬, Gotabhaya Ranasinghe, Markus Peter Schlaich, Paul K. Whelton, Gian Luca Di Tanna, Aletta Elisabeth Schutte, Jackson T. Wright, M. B. F. Rahuman, Rashmi Pant, Neil R Poulter, Asita de Silva, Abdul Salam, Gamini Galappatthy, Krzysztof Narkiewicz, Mathangi Shanthakumar, Amit Kumar, W. Uluwattage, A. P. de Silva, Prashant Lakshman, Xiaoqiu Liu, L Rasnayake, Thambyaiah Kandeepan, G Mayurathan
article en

Abstract

In a population with mild-to-moderate hypertension, long-term therapy with GMRx2-based treatment achieved high levels of BP control and was well tolerated.Trial registration: NCT04518306.

Global HeartVol. 20(1)
Tulane University (US), University of Kelaniya (LK), University of Applied Sciences and Arts of Southern Switzerland (CH), University of Tennessee Health Science Center (US), Manipal Academy of Higher Education (IN), The University of Western Australia (AU), The George Institute for Global Health (GB), Utrecht University (NL), University Hospitals of Cleveland (US), Jaffna Teaching Hospital (LK), Teaching Hospital Kandy (LK), University Medical Center Utrecht (NL), University of Alabama at Birmingham (US), Colombo North Teaching Hospital (LK), National Hospital of Sri Lanka (LK), The George Institute for Global Health (AU), George Institute for Global Health (IN), Karamay Central Hospital (CN), George Institute for Global Health (CN), Kushiro City General Hospital (JP), University College London (GB), Imperial College London (GB), Gdańsk Medical University (PL), University of Abuja (NG), Bayero University Kano (NG)
George Institute for Global Health
Openalex Percentile: Top 57%
Diabetes Treatment and Management
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