Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension
In a population with mild-to-moderate hypertension, long-term therapy with GMRx2-based treatment achieved high levels of BP control and was well tolerated.Trial registration: NCT04518306.
Authors
- Suzanne Oparil (ORCID: https://orcid.org/0000-0002-7505-2599)
- Christopher Gianacas (ORCID: https://orcid.org/0000-0003-0594-9007)
- William C. Cushman (ORCID: https://orcid.org/0000-0001-7162-2972)
- Diederick E. Grobbee (ORCID: https://orcid.org/0000-0003-4472-4468)
- Godwin Constantine (ORCID: https://orcid.org/0000-0003-0840-8564)
- Wilko Spiering (ORCID: https://orcid.org/0000-0002-2493-6407)
- Anthony Rodgers (ORCID: https://orcid.org/0000-0003-1282-1896)
- Dike Bevis Ojji (ORCID: https://orcid.org/0000-0002-2084-1988)
- Bryan Williams (ORCID: https://orcid.org/0000-0002-8094-1841)
- Tiago Pereira (ORCID: https://orcid.org/0000-0002-8574-832X)
- Mahmoud Umar Sani (ORCID: https://orcid.org/0000-0001-8946-129X)
- Ruth S. Freed (ORCID: https://orcid.org/0000-0003-4170-1746)
- T. Kumanan (ORCID: https://orcid.org/0000-0001-5735-4713)
- Gotabhaya Ranasinghe (ORCID: https://orcid.org/0000-0002-9339-5368)
- Markus Peter Schlaich (ORCID: https://orcid.org/0000-0002-1765-0195)
- Paul K. Whelton (ORCID: https://orcid.org/0000-0002-2225-383X)
- Gian Luca Di Tanna (ORCID: https://orcid.org/0000-0002-5470-3567)
- Aletta Elisabeth Schutte (ORCID: https://orcid.org/0000-0001-9217-4937)
- Jackson T. Wright
- M. B. F. Rahuman (ORCID: https://orcid.org/0009-0003-6071-7839)
- Rashmi Pant (ORCID: https://orcid.org/0000-0003-3424-1155)
- Neil R Poulter (ORCID: https://orcid.org/0000-0002-6292-997X)
- Asita de Silva (ORCID: https://orcid.org/0000-0003-2544-6861)
- Abdul Salam (ORCID: https://orcid.org/0000-0002-5870-7936)
- Gamini Galappatthy (ORCID: https://orcid.org/0000-0001-6247-8681)
- Krzysztof Narkiewicz (ORCID: https://orcid.org/0000-0001-5949-5018)
- Mathangi Shanthakumar
- Amit Kumar
- W. Uluwattage
- A. P. de Silva
- Prashant Lakshman
- Xiaoqiu Liu
- L Rasnayake
- Thambyaiah Kandeepan
- G Mayurathan
Institutions
- Tulane University (US)
- University of Kelaniya (LK)
- University of Applied Sciences and Arts of Southern Switzerland (CH)
- University of Tennessee Health Science Center (US)
- Manipal Academy of Higher Education (IN)
- The University of Western Australia (AU)
- The George Institute for Global Health (GB)
- Utrecht University (NL)
- University Hospitals of Cleveland (US)
- Jaffna Teaching Hospital (LK)
- Teaching Hospital Kandy (LK)
- University Medical Center Utrecht (NL)
- University of Alabama at Birmingham (US)
- Colombo North Teaching Hospital (LK)
- National Hospital of Sri Lanka (LK)
- The George Institute for Global Health (AU)
- George Institute for Global Health (IN)
- Karamay Central Hospital (CN)
- George Institute for Global Health (CN)
- Kushiro City General Hospital (JP)
- University College London (GB)
- Imperial College London (GB)
- Gdańsk Medical University (PL)
- University of Abuja (NG)
- Bayero University Kano (NG)
Publication Details
- Journal
- Global Heart
- Published
- 2025-10-31
- DOI
- https://doi.org/10.5334/gh.1481
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- George Institute for Global Health