Synthesis and Characterization of Novel Potassium Ethane-1,2-diylbis((2-bromobenzyl) carbamodithioate) Complexes, Along with an Investigation of their Biological Activity.

In this study, the synthesized ligand and its complexes demonstrated notable antibacterial activity against several pathogenic bacteria. The Spectroscopic and analytical characterisation of a group of metallic complexes (II) belonging to the ligand dithiocarbamate were prepared, the ligand was prepared from three stepes. Follow: I. preparation of Schiff base by reaction Ethelinediamin with Bromobenzaldehyde. II. Reaction the product's Schiff base with Soduimborohydrate to yield Secondary Amin. III. Theproduct secondary amin reacted with carbondisulfide to producted ligand, which reacted with metal ion to yield dithiocarbamate complexes. The spatial shape around the ionic centers of the complexes was determined using a number of physic-chemical and spectroscopic techniques, including. UV-Vis, 1H-NMR, FTIR, mass spectrometers, melting points, and conductivity. This analytical and spectroscopic data showed that the MnII, FeII, CoII, NiII, CuII, and ZnII ions had a tetrahedral shape and square planar geometry with Ni(II) complexes. The antibacterial activity of ligands and complexes was evaluated with two types of bacteria: Staphylococcus aureus (gram-positive) and Escherichia coli (gram-negative). Zone of inhibition assays further supported these findings showing clear inhibition Zone of up to 15mm around the complexes. May be its disrupt bacterial cell membrane integrity and inhibit essential complexesas effective antibacterial agent.