Bioinformatics and experimental animal model reveal the prognostic value of immunogenic cell death-related proteins in idiopathic pulmonary fibrosis

We developed and validated a novel ICD-related gene signature capable of predicting prognosis in IPF patients. The three-gene risk model may serve as a promising tool for risk stratification and personalized treatment planning in IPF.

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Publication Details

Journal
Journal of Thoracic Disease
Published
2025-10-01
DOI
https://doi.org/10.21037/jtd-2025-616
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

Bioinformatics and experimental animal model reveal the prognostic value of immunogenic cell death-related proteins in idiopathic pulmonary fibrosis

Cong Liang, Yihan Lin, Hui Ren, Guangjian Zhang et al.
Journal of Thoracic Disease
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Bioinformatics and experimental animal model reveal the prognostic value of immunogenic cell death-related proteins in idiopathic pulmonary fibrosis

Cong Liang, Yihan Lin, Hui Ren, Guangjian Zhang, Meng Li, Huanhuan Dong, Zhiying Wang, Jingyang Sun, Rongxuan Jiang, Meng Fan, Liren Hou, Yanpeng Zhang
article en

Abstract

We developed and validated a novel ICD-related gene signature capable of predicting prognosis in IPF patients. The three-gene risk model may serve as a promising tool for risk stratification and personalized treatment planning in IPF.

Journal of Thoracic DiseaseVol. 17(10)
First Affiliated Hospital of Xi'an Jiaotong University (CN)
Openalex Percentile: Top 54%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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