Wuhu decoction regulates ROS/AMPK/mTOR pathway-mediated dendritic cells autophagy and pyroptosis for the treatment of respiratory syncytial virus-induced asthma
WHD may activate DCs autophagy through the ROS/AMPK/mTOR axis, inhibit NLRP3 inflammasome-induced cell pyroptosis, and thus prevent and treat RSV-induced asthma in mice.
Authors
- Jing Luo (ORCID: https://orcid.org/0000-0002-3211-4331)
- Yi Ding (ORCID: https://orcid.org/0000-0002-9468-5930)
- Jinglei Liu (ORCID: https://orcid.org/0000-0002-5388-6920)
- Mengqing Wang (ORCID: https://orcid.org/0009-0003-3506-002X)
- Yaxiong Deng (ORCID: https://orcid.org/0000-0001-6433-3232)
- Yan Hu
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Changsha University (CN)
- Guangzhou Development Zone Hospital (CN)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/jtd-2025-881
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81