Prognostic significance of the 9th TNM lung cancer staging system in SCLC

This retrospective analysis confirmed a significant difference in prognosis between the N<sub>2a</sub> and N<sub>2b</sub> subgroups in the 9th edition. No statistically significant difference was observed between the M1c1 and M<sub>1c2</sub> subgroups. The present study suggests that the 9th edition of TNM requires further validation using external datasets, and factors such as the number of metastatic lesions in a single organ may also be included in future TNM classification systems.

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Publication Details

Journal
Journal of Thoracic Disease
Published
2025-10-01
DOI
https://doi.org/10.21037/jtd-2025-1031
Primary Topic
Lung Cancer Research Studies
Type
article
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article

Prognostic significance of the 9th TNM lung cancer staging system in SCLC

Ruru Sun, Yansu Wang, Yao Fu, Yang Liu et al.
Journal of Thoracic Disease
Lung Cancer Research Studies
article

Prognostic significance of the 9th TNM lung cancer staging system in SCLC

Ruru Sun, Yansu Wang, Yao Fu, Yang Liu, Shuang Zhang, Shuang Li
article en

Abstract

This retrospective analysis confirmed a significant difference in prognosis between the N<sub>2a</sub> and N<sub>2b</sub> subgroups in the 9th edition. No statistically significant difference was observed between the M1c1 and M<sub>1c2</sub> subgroups. The present study suggests that the 9th edition of TNM requires further validation using external datasets, and factors such as the number of metastatic lesions in a single organ may also be included in future TNM classification systems.

Journal of Thoracic DiseaseVol. 17(10)
Jilin Province Tumor Hospital (CN)
Openalex Percentile: Top 57%
Lung Cancer Research Studies
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