Clinical and dosimetric risk factors for radiation pneumonitis after proton therapy in lung cancer patients: a retrospective study

Dosimetric parameters, specifically V10, V20, V30, V40, V50, V60, and MLD of the ipsilateral lung, along with V40, V50, and V60 of the total lung, are associated with grade ≥2 RP in lung cancer patients receiving proton radiotherapy. By identifying the risk factors associated with RP, clinicians can more effectively optimize treatment regimens, mitigate adverse effects in patients, and enhance overall treatment outcomes.

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Publication Details

Journal
Journal of Thoracic Disease
Published
2025-10-01
DOI
https://doi.org/10.21037/jtd-2025-776
Primary Topic
Effects of Radiation Exposure
Type
article
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article

Clinical and dosimetric risk factors for radiation pneumonitis after proton therapy in lung cancer patients: a retrospective study

Zhuping Su, Xiaoming Lu, Shuanghu Yuan, Hongyan Zhang et al.
Journal of Thoracic Disease
Effects of Radiation Exposure
article

Clinical and dosimetric risk factors for radiation pneumonitis after proton therapy in lung cancer patients: a retrospective study

Zhuping Su, Xiaoming Lu, Shuanghu Yuan, Hongyan Zhang, Ning Liu, Tao Zhou, Nannan Wei
article en

Abstract

Dosimetric parameters, specifically V10, V20, V30, V40, V50, V60, and MLD of the ipsilateral lung, along with V40, V50, and V60 of the total lung, are associated with grade ≥2 RP in lung cancer patients receiving proton radiotherapy. By identifying the risk factors associated with RP, clinicians can more effectively optimize treatment regimens, mitigate adverse effects in patients, and enhance overall treatment outcomes.

Journal of Thoracic DiseaseVol. 17(10)
University of Science and Technology of China (CN)
Openalex Percentile: Top 54%
Effects of Radiation Exposure
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