Intrathecal pemetrexed in patients with epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) resistant refractory leptomeningeal metastasis lung adenocarcinoma: a retrospective study
This study suggests that intrathecal pemetrexed can be a viable salvage treatment for refractory meningeal metastasis in EGFR-TKI-resistant lung adenocarcinoma.
Authors
- Xiaohua Liang (ORCID: https://orcid.org/0000-0003-3867-9779)
- Rongrong Yao (ORCID: https://orcid.org/0009-0006-2369-561X)
- Hao Dong Lin
- Jing Li (ORCID: https://orcid.org/0000-0002-7169-5167)
- Xinli Zhou (ORCID: https://orcid.org/0000-0001-5430-8594)
- Mengxi Ge
Institutions
- Fudan University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2025-10-01
- DOI
- https://doi.org/10.21037/jtd-2025-1303
- Citations
- 1
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52