Melatonin Reduces Radiation-induced Apoptosis Through Change of bax and bcl-2 Expression in Peripheral Blood Lymphocytes
Melatonin can protect rat lymphocytes from x-radiation-triggered apoptosis by modulating bcl-2 and bax expression. Therefore, melatonin could serve as a potential radio-protective agent, making it a candidate for use alongside radiation in clinical trials.
Authors
- Elham Motallebzadeh
- Sayyed Alireza Talaei (ORCID: https://orcid.org/0000-0001-9781-7313)
- Mehran Mohseni (ORCID: https://orcid.org/0000-0002-6685-1743)
Institutions
- Isfahan University of Medical Sciences (IR)
- Kashan University of Medical Sciences (IR)
Publication Details
- Journal
- Advanced Biomedical Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.4103/abr.abr_99_24
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.00