Conditioned medium from stem cells of human exfoliated deciduous teeth ameliorates mouse ovalbumin-specific allergic dermatitis
SHED-CM shows significant therapeutic potential for AD-like symptom, effectively modulating immune response and enhancing skin barrier restoration. Our findings offer a new approach for developing novel, targeted therapies for inflammatory skin disorders.
Authors
- Tsuyoshi Arai
- Fumiya Kano
- Linze Xia
- Akihito Yamamoto (ORCID: https://orcid.org/0000-0002-9206-1243)
- Tomonori Iwasaki (ORCID: https://orcid.org/0000-0003-3919-4714)
- Cheng Ding (ORCID: https://orcid.org/0000-0003-2295-6532)
- Yang Xu
- Noboru Hashimoto
- Houjun Lao
- Yifei Wang (ORCID: https://orcid.org/0009-0001-2961-9996)
Institutions
- Tokushima University (JP)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1186/s13287-025-04735-2
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Tokushima
- Japan Society for the Promotion of Science