A qualitative burden of disease study in patients with invasive Escherichia coli disease aged ≥ 60 years in the United States
IED was shown to cause substantial physical, social, and psychological impacts in patients. This burden was especially apparent in review of patient self-reports for concepts that are part of generic HRQoL instruments (SF-36, EQ-5D), and patients also frequently reported neurological/mental impacts. Further, this study provides valuable qualitative data that may be useful for future research in developing a disease-specific instrument for the assessment of HRQoL in patients with IED.
Authors
- Mark A. Schmidt (ORCID: https://orcid.org/0000-0002-7440-7183)
- Judy Donald
- Michal Sarnecki (ORCID: https://orcid.org/0000-0001-7035-0020)
- Jeroen Geurtsen (ORCID: https://orcid.org/0000-0002-8234-846X)
- Inga Gruß (ORCID: https://orcid.org/0000-0002-6167-0548)
- Thomas Verstraeten (ORCID: https://orcid.org/0000-0002-4507-7285)
- James V. Davis
- Kelly McQuarrie (ORCID: https://orcid.org/0000-0002-2362-1163)
- E. Carrió
- Luis Hernandez Pastor
- Joachim Doua (ORCID: https://orcid.org/0000-0002-3503-3596)
- Cristina Valencia (ORCID: https://orcid.org/0000-0003-0008-4980)
- Antoine C. El Khoury
Institutions
- Johnson & Johnson (United States) (US)
- Johnson & Johnson (Switzerland) (CH)
- Human Vaccines Project Europe (NL)
- Johnson Research & Development (United States) (US)
- Kaiser Permanente Center for Health Research (US)
- Johnson & Johnson (Brazil) (BR)
- KU Leuven (BE)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1186/s12879-025-11628-5
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00