Safety and efficacy of phrenic nerve stimulation: A case series at the University of Oklahoma and review of the international literature
PNS can be an effective method for achieving ventilator independence in carefully selected patients, particularly those with high cervical SCIs. However, its efficacy in NDDs appears limited. PNS appears to be most effective in a specific subset of individuals, which suggests that proper patient selection is a key element to the success of this procedure. While PNS shows promise, larger controlled studies are needed to establish the long-term efficacy and safety profile of this procedure across various patient populations.
Authors
- Houssein Youness (ORCID: https://orcid.org/0000-0003-4892-3640)
- Andrew Jea
- Abdurrahman F. Kharbat (ORCID: https://orcid.org/0000-0002-8790-367X)
- Xiaochun Zhao (ORCID: https://orcid.org/0000-0002-9069-5891)
- Kishore Balasubramanian (ORCID: https://orcid.org/0000-0002-7271-7022)
- Maida Hafiz
- Marianne Kimmell
Institutions
- Texas A&M Health Science Center (US)
- Oklahoma City University (US)
- Pulmonary Associates (US)
- University of Oklahoma Health Sciences Center (US)
- University of Oklahoma (US)
Publication Details
- Journal
- Surgical Neurology International
- Published
- 2025-10-31
- DOI
- https://doi.org/10.25259/sni_406_2025
- Citations
- 1
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84