RWD18 ANALYSIS OF HEALTH-RELATED QUALITY OF LIFE AND ITS INFLUENCING FACTORS IN CHINESE PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY

Among 356 stroke patients enrolled, 222 (62.4%) had hemorrhagic strokes, while 134 (37.6%) had ischemic strokes.Notably, 327 (92%) were hypertensive, and 158 (44.4%) sought delayed medical attention after symptom onset.Hemorrhagic stroke patients had more severe National Institutes of Health Stroke Scale scores (NIHSS) (p,0.001) and higher early mortality (n=33, (14.9%)) compared to ischemic stroke (n=10, (7.5%)).Risk factors such as hypertension, non-adherence to antihypertensives, smoking, alcohol consumption, and COVID-19 vaccination were associated with higher odds of hemorrhagic stroke.Advanced age, history of stroke, type 2 diabetes mellitus, atrial fibrillation, low high-density lipoprotein cholesterol levels, and hypertensive-diabetics were more linked to ischemic stroke (p,0.05).Conclusions: This real-world study highlights a higher burden of hemorrhagic stroke in Northeast India, with modifiable risk factors such as hypertension and smoking playing a central role.The strong association with irregular antihypertensive use underscores the urgent need for targeted public health interventions to improve medication adherence and control risk factors.Region-specific strategies are essential to reduce stroke incidence and recurrence, and larger multicenter studies are warranted to validate these findings.