Association between S-ketamine induced changes in glutamate levels in the pregenual anterior cingulate cortex and plasma brain-derived neurotrophic factor in healthy subjects
These findings provide initial <i>in vivo</i> support for the hypothesis that ketamine's effects on BDNF dynamics are linked to its glutamatergic action.
Authors
- Volkmar Leßmann (ORCID: https://orcid.org/0000-0002-6863-323X)
- Zümrüt Duygu Şen (ORCID: https://orcid.org/0000-0001-8246-5650)
- Tanja Brigadski (ORCID: https://orcid.org/0000-0001-9816-3964)
- Martin A. Walter (ORCID: https://orcid.org/0000-0001-6487-5349)
- Lena Vera Danyeli (ORCID: https://orcid.org/0000-0003-1504-7533)
- Meng Li
- Leonard Marx
Institutions
- Jena University Hospital (DE)
- University of Applied Sciences Kaiserslautern (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-10-31
- DOI
- https://doi.org/10.3389/fpsyt.2025.1662051
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Leibniz-Gemeinschaft