Isolation and characterisation of AFP+/DLK1+ double-positive hepatic stem/progenitor-like cells from fibrotic partial hepatectomy model
AFP and DLK1 serve as potential markers for selecting HSPC-like populations from the fibrotic PHx model. Our findings indicate that the fibrotic liver exhibits the most vigorous regenerative activity at 48 h after PHx, making it the optimal period for the isolation and extraction of HSPC-like cells which refers only to marker expression and proliferation, the relevance of the findings presented herein remains to be further verified.
Authors
- Tegshjargal Badamjav (ORCID: https://orcid.org/0000-0001-9982-949X)
- Bayar Hexig (ORCID: https://orcid.org/0000-0003-0280-1170)
- Batbold Batsaikhan (ORCID: https://orcid.org/0000-0003-3109-2166)
- Shuangliang Sun
- Namur Narid
- Urjims Xu
- Dunfu Suo
Institutions
- Inner Mongolia Agricultural University (CN)
- Inner Mongolia University (CN)
- Mongolian National University (MN)
- Mongolian National University of Medical Sciences (MN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1186/s13287-025-04728-1
- Citations
- 1
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- Inner Mongolia University