Investigating apoptosis in peripheral blood mononuclear cells among the elderly in the post-COVID-19 era

COVID-19 may cast a long immunological shadow in the elderly, with persistent PBMC apoptosis representing a novel facet of post-viral immune dysregulation. Flow cytometry reveals a unique apoptotic phenotype that could serve as a biomarker for long-term immune health and guide post-pandemic clinical management strategies for aging populations.

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Publication Details

Journal
BMC Immunology
Published
2025-10-31
DOI
https://doi.org/10.1186/s12865-025-00769-6
Primary Topic
Phagocytosis and Immune Regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Investigating apoptosis in peripheral blood mononuclear cells among the elderly in the post-COVID-19 era

Elaheh Abiri, Najmeh Hemmatian
BMC Immunology
Phagocytosis and Immune Regulation
article

Investigating apoptosis in peripheral blood mononuclear cells among the elderly in the post-COVID-19 era

Elaheh Abiri, Najmeh Hemmatian
article en

Abstract

COVID-19 may cast a long immunological shadow in the elderly, with persistent PBMC apoptosis representing a novel facet of post-viral immune dysregulation. Flow cytometry reveals a unique apoptotic phenotype that could serve as a biomarker for long-term immune health and guide post-pandemic clinical management strategies for aging populations.

BMC ImmunologyVol. 26(1)
Damghan University (IR), Semnan University of Medical Sciences (IR)
Openalex Percentile: Top 67%
Phagocytosis and Immune Regulation
DOIOpen Access PDFOpenAlex
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Investigating apoptosis in peripheral blood mononuclear cells among the elderly in the post-COVID-19 era — Elaheh Abiri, Najmeh Hemmatian · BMC Immunology (2025) | TGRS Research Map | TGRS