Development and applications of heterogeneous chiral bifunctional alkaloid-thioureas as recyclable organocatalysts
The development of heterogeneous chiral catalysts is a growing research field, offering recyclable alternatives to their homogeneous counterparts. With the aim of identifying a general and reliable methodology to access highly recyclable catalysts, herein, a structure-activity relationship study of chiral base-thiourea bifunctional catalysts is reported. The solid-supported catalysts have been benchmarked using well-known model reactions, allowing recycling of the catalyst up to 15 times without a decrease in the chiral induction properties.
Authors
- Javier Vicario (ORCID: https://orcid.org/0000-0002-8976-0991)
- Aitor Maestro (ORCID: https://orcid.org/0000-0003-4726-9675)
- Patrick Y. Toullec (ORCID: https://orcid.org/0000-0003-0376-5052)
- Xabier del Corte (ORCID: https://orcid.org/0000-0002-6973-0912)
- Ainara Pellicer
- Nora Aranburu (ORCID: https://orcid.org/0000-0001-5730-9867)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université de Bordeaux (FR)
- University of the Basque Country (ES)
- Institut des Sciences Moléculaires (FR)
- Institut Polytechnique de Bordeaux (FR)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob01582k
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00